- Network: Fox, Fox Sports 1, UFC Fight Pass
- Venue: Gila River Arena
- Location: Glendale, Arizona
- Event Date: April 14, 2018 7:30PM
Justin Gaethje (18-1) vs. Dustin Poirier (22-5, 1NC)
Carlos Condit (30-11) vs. Alex Oliveira (18-4-1)
Wilson Reis (22-8) vs. John Moraga (18-6)
Brad Tavares (16-4) vs. Krzysztof Jotko (19-3)
Yushin Okami (34-11) vs. Dhiego Lima (12-6)
Luke Sanders (11-2) vs. Patrick Williams (8-5)
Michelle Waterson (14-6) vs. Cortney Casey (7-5)
Antonio Carlos Jr. (9-2, 1NC) vs. Tim Boetsch (21-11)
Shana Dobson (3-1) vs. Lauren Mueller (4-0)
Ricky Rainey (13-4) vs. Muslim Salikhov (13-2)
Alejandro Perez (19-6-1) vs. Matthew Lopez (10-2)
Israel Adesanya (12-0) vs. Marvin Vettori (12-3-1)
Gilbert Burns (12-2) vs. Dan Moret (13-3)
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