- Network: WWE Network
- Venue: WWE ThunderDome
- Location: Tampa, Florida
- Event Date: February 21, 2021 7:00PM
WWE Championship - Elimination Chamber
Drew McIntyre (c) vs. AJ Styles vs. Kofi Kingston vs. Randy Orton vs. Sheamus vs. Jeff Hardy
WWE Universal Championship
Roman Reigns (c) vs. Winner of SmackDown Elimination Chamber Match
WWE Universal Championship #1 Contender - Elimination Chamber
Cesaro vs. Daniel Bryan vs. Kevin Owens vs. Sami Zayn vs. King Corbin vs. Jey Uso
WWE Raw Women's Championship
Asuka (c) vs. Lacey Evans (w/ Ric Flair)
WWE United States Championship
Bobby Lashley (c) vs. Riddle vs. Keith Lee
WWE Women's Tag Team Championships
Nia Jax & Shayna Baszler (c) vs. Sasha Banks & Bianca Belair