- Rhea Ripley had the most eliminations of any wrestler in 2021, with seven.
- Five of the top 9 times in women's Rumble history were from the 2021 field.
- Shayna Baszler's six eliminations give her 14 all-time, which is a women's record.
- VIctoria and Jillian Hall had their first WWE matches in over ten years at the Royal Rumble.
- Bianca Belair spent 56:49 in the Royal Rumble, a women's record, beating Natalya's previous record.
- Bianca Belair is the first woman to win from the #3 spot, or any spot lower than 17.
- Carmella, Dana Brooke, Liv Morgan, Mandy Rose, Naomi, Natalya and Tamina have been in every women's Royal Rumble match.
- Bianca Belair tied Charlotte Flair's record for eliminations by a women's winner, with four.
- Charlotte Flair now has the cumulative Royal Rumble time record for women with 1:51:05.
- Carmella was the shortest time spent in the Rumble at 45 seconds, the sixth shortest ever.
- Kane has now eliminated 46 wrestlers across three different characters to extend his Royal Rumble record. The next closest active wrestler is Braun Strowman at 36, though 13 were in the Greatest Royal Rumble. The next closest is Roman Reigns at 32.
- Kane joins Edge as the only wrestlers to be in Royal Rumbles in the 90s, 2000s, 2010s and 2020s. They are joined by Jim Duggan and Shawn Michaels as four-decade Royal Rumblers.
- Kane also became the first wrestler to appear in 20 Royal Rumbles. Dolph Ziggler moved into sole possesion of second place with 14.
- Seth Rollins, Big E, Damian Priest and Braun Strowman all eliminated four wrestlers.
- Edge is the first WWE Hall of Famer to win a Royal Rumble.
- Edge became the third person to win from the number one spot, which is now second most. However, the number two spot has seen two winners, meaning that starting the Royal Rumble is the likeliest to win one.
- Edge and Randy Orton both technically cracked the top 10 longest men's times in a Royal Rumble match ever.
- Edge and Orton are the third duo to go from numbers 1 and 2 and make it all the way to the end of the Royal Rumble. All of these have featured competitors going backstage, or a shorter Royal Rumble match (1995).
- Randy Orton has now technically spent 4:31:49 in a Royal Rumble, second to Chris Jericho's 4:59:33.
- The Hurricane was the quickest elimination at 30 seconds.
