- Network: ESPN, ESPN+
- Venue: Toyota Center
- Location: Houston, Texas
- Event Date: August 7, 2021 4:00AM
Main Card (10pm EST., ESPN+ Pay-Per-View)
Vacant UFC Interim Heavyweight Championship
Derrick Lewis (25-7) vs. Cyril Gane (9-0)
Jose Aldo (29-7) vs. Pedro Munhoz (19-5)
Yadong Song (16-5-1) vs. Casey Kenney (16-3-1)
Vicente Luque (20-7-1) vs. Michael Chiesa (17-4)
Tecia Torres (12-5) vs. Angela Hill (13-9)
Preliminary Card (8pm EST., ESPN 2)
Bobby Green (27-11-1) vs. Rafael Fiziev (8-1)
Drako Rodriguez (7-2) vs. Vince Morales (9-5)
Ed Herman (25-14) vs. Alonzo Menifield (10-2)
Karolina Kowalkiewicz (12-6) vs. Jessica Penne (13-5)
Early Preliminary Card (6pm EST., ESPN+)
Johnny Munoz Jr. (10-1) vs. Jamey Simmons (7-3)
Victoria Leonardo (8-3) vs. Melissa Gatto (6-0-2)
Manel Kape (15-6) vs. Ode Osbourne (9-3)
Miles Johns (11-1) vs. Anderson Dos Santos (21-8)
